IMPORTANCE OF EARLY DETECTION OF MIXED ENDODONTIC - PERIODONTAL LESIONS IN DENTAL PRACTICE A ‘LETTER TO THE EDITOR’
Abstract
We read with great interest the growing body of literature addressing the complex
interrelationship between pulpal and periodontal diseases. Among these, mixed endodontic
periodontal lesions represent a particularly challenging clinical entity that continues to pose
diagnostic and therapeutic dilemmas in routine dental practice. We would like to highlight the
importance of early detection of these lesions and underscore its implications from both a clinical
and publication perspective.
Mixed endodontic–periodontal lesions arise due to the close anatomical and functional
relationship between the dental pulp and the periodontium.1 Communication pathways such as
apical foramina, lateral and accessory canals, dentinal tubules, and developmental anomalies
facilitate the spread of infection between these two tissues.1 As a result, pathology originating in
either the pulp or the periodontium may secondarily involve the other, often leading to overlapping
clinical and radiographic features. This intricate interconnection makes early diagnosis both
critical and challenging.2
References
Simon JH, Glick DH, Frank AL. The relationship of endodontic–periodontic lesions. J
Periodontol. 1972;43(4):202–8.
Rotstein I, Simon JH. Diagnosis, prognosis and decision-making in the treatment of
combined periodontal–endodontic lesions. Periodontol 2000. 2004;34:165–203.
Herrera D, Roldán S, Sanz M. The periodontal–endodontic controversy. Periodontol 2000.
;58(1):7–21.
Abbott PV, Salgado JC. Strategies for the endodontic management of concurrent
endodontic and periodontal diseases. Aust Dent J. 2009;54(Suppl 1):S70–85.
Meng HX. Periodontal abscess. Ann Periodontol. 1999;4(1):79–82.
Zehnder M, Gold SI, Hasselgren G. Pathologic interactions in pulpal and periodontal
tissues. J Clin Periodontol. 2002;29(8):663–71.
Hargreaves KM, Berman LH. Cohen’s Pathways of the Pulp. 11th ed. St Louis: Elsevier;
Nair PN. On the causes of persistent apical periodontitis: a review. Int Endod J.
;39(4):249–81.
Seltzer S, Bender IB. The interrelationship of pulp and periodontal disease. Oral Surg Oral
Med Oral Pathol. 1963;16:1474–90.
Al-Fouzan KS. A new classification of endodontic–periodontal lesions. Int Endod J.
;47(10):971–80.
von Arx T, Bosshardt D. Endodontic–periodontal lesions: diagnostic challenges and
clinical concepts. Swiss Dent J. 2015;125(10):1111–23.
Jansson L, Ehnevid H, Lindskog S, Blomlöf L. Relationship between periapical and
periodontal status. J Clin Periodontol. 1993;20(2):117–23.
Ricucci D, Siqueira JF Jr. Biofilms and apical periodontitis: study of prevalence and
association with clinical findings. J Endod. 2010;36(8):1277–88.
Kwon EY, Cho YJ, Kim SG, Park JC. Clinical decision-making and prognosis of
endodontic–periodontal lesions. Restor Dent Endod. 2014;39(4):259–65.
Patel S, Durack C, Abella F, Roig M, Shemesh H, Lambrechts P, et al. Cone beam
computed tomography in Endodontics – a review. Int Endod J. 2015;48(1):3–15.

