PHYTOGENIC GREEN SYNTHESIS OF MULTIFUNCTIONAL MAGNETIC NANOCOMPOSITES FOR BIOMEDICAL, CATALYTIC, AND ENVIRONMENTAL APPLICATIONS
Keywords:
Green synthesis; Magnetic nanocomposites; Curry leaf extract (Murraya koenigii); Biomedical applications; Environmental remediation; Photocatalysis; Heavy metal adsorption; Antibacterial activity; Sustainable nanotechnology.,,Abstract
As the demand for sustainable productions of nanomaterials grows, the development of
environmentally friendly methods that reduce or completely remove the use of harmful
chemicals and improve the functionality of the materials is accelerating. The current study
introduces a green synthesis approach for the preparation of multifunctional magnetic
nanocomposites through the natural reducing, stabilizing and capping agent Murraya koenigii
(curry leaf) extract. Phytochemicals such as polyphenols, flavonoids, alkaloids, and terpenoids
found in the extract play a role in the dispersion of magnetic nanoparticles to form uniformly
distributed particles with improved physicochemical stability. The structural, morphological,
magnetic, elemental and thermal properties of the synthesized nanocomposites were
comprehensively assessed by performing various characterization techniques such as UV
Visible spectroscopy, Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction
(XRD), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM),
Energy Dispersive X-ray Spectroscopy (EDX), Vibrating Sample Magnetometry (VSM) and
Thermogravimetric Analysis (TGA). The composites developed are investigated for their
multifunctional use in biomedical and environmental applications. Through a series of
biomedical studies, the researchers found that the compounds exhibited strong antioxidant
properties, high efficacy against Gram-positive and Gram-negative bacteria strains, good
biocompatibility, and improved drug-loading potential, all of which suggest their application
in targeted drug delivery, fabrication of antimicrobial coatings, and biomedical diagnostics.
The environmental studies showed excellent photocatalytic degradation ability for organic dye
pollutants, high adsorption ability toward heavy metal ions, and excellent magnetic
recoverability for repeated use without much loss of catalytic activity. The magnetic properties
enable the nanocomposites to be easily separated from aqueous media, thus enhancing the
operational efficiency and reducing secondary contamination. The outcomes reveal that curry
leaf extract could be used as a very efficient, renewable and environmentally friendly precursor
for the preparation of magnetic nanocomposites of high performance which possess high
stability and multifunctionality. The green chemistry approach combined with magnetic
nanotechnology offers a platform for the development of sustainable materials for advanced
biomedical therapies, environmental remediation, wastewater treatment, and catalytic
applications at a lower cost and at a larger scale. This work points out the high potential
applications of magnetic nanocomposites of plants as new multifunctional materials, which can
be used for solving health and environmental problems and for sustainable nanomanufacturing
methods.
References
Karunakaran, S., Ramanujam, S., & Gurunathan, B. (2018). Green synthesised iron and
iron-based nanoparticle in environmental and biomedical application: A review. IET
Nanobiotechnology, 12(8), 1003–1008. https://doi.org/10.1049/iet-nbt.2018.5048.
Machado, S., Pinto, S. L., Grosso, J. P., Nouws, H. P. A., Albergaria, J. T., & Delerue
Matos, C. (2013). Green production of zero-valent iron nanoparticles using tree leaf
extracts. Science of the Total Environment, 445–446, 1–8.
Wang, Y. X. J. (2011). Superparamagnetic iron oxide based MRI contrast agents:
Current status of clinical application. Quantitative Imaging in Medicine and Surgery,
(1), 35–40.
Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Vander Elst, L., & Muller, R. N.
(2008). Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization,
physicochemical characterizations, and biological applications. Chemical Reviews,
(6), 2064–2110.
Lu, A. H., Salabas, E. L., & Schüth, F. (2007). Magnetic nanoparticles: Synthesis,
protection, functionalization, and application. Angewandte Chemie International
Edition, 46(8), 1222–1244.
Wu, W., He, Q., & Jiang, C. (2008). Magnetic iron oxide nanoparticles: Synthesis and
surface functionalization strategies. Nanoscale Research Letters, 3, 397–415.
Yew, Y. P., Shameli, K., Miyake, M., et al. (2020). Green biosynthesis of
superparamagnetic magnetite Fe₃O₄ nanoparticles and biomedical applications in
targeted anticancer drug delivery system: A review. Arabian Journal of Chemistry,
(1), 2287–2308. https://doi.org/10.1016/j.arabjc.2018.04.013.
Jeevanandam, J., Barhoum, A., Chan, Y. S., Dufresne, A., & Danquah, M. K. (2018).
Review on nanoparticles and nanostructured materials: History, sources, toxicity and
regulations. Beilstein Journal of Nanotechnology, 9, 1050–1074.
Khan, I., Saeed, K., & Khan, I. (2019). Nanoparticles: Properties, applications and
toxicities. Arabian Journal of Chemistry, 12(7), 908–931.
silver
Roy, A., Bulut, O., Some, S., Mandal, A. K., & Yilmaz, M. D. (2019). Green synthesis
of
nanoparticles:
Biomolecule–nanoparticle organizations targeting
antimicrobial activity. RSC Advances, 9, 2673–2702.
Parlayici, Ş., Pehlivan, E., & Avci, A. (2021). Sustainable plant and microbes-mediated
preparation of Fe₃O₄ nanoparticles and industrial application of its chitosan, starch,
cellulose, and dextrin-based nanocomposites as catalysts. International Journal of
Biological
Macromolecules,
https://doi.org/10.1016/j.ijbiomac.2021.02.183.
,
–447.
Gnanaprakasam, A., Sivakumar, V. M., Thirumarimurugan, M., & Kannadasan, T.
(2015). Influencing parameters in the photocatalytic degradation of organic pollutants.
Journal of Environmental Chemical Engineering, 3(1), 25–35.
Ilyas, H., Tomar, S., Raghav, H., et al. (2026). Recent developments in green synthesis
of nanoparticles using Murraya koenigii for multifunctional applications. Discover
Materials.
Phoenix: International Multidisciplinary Research Journal
Vol 1, Jan-March, 2022
ISSN: 2583-6897
Abbas, M., Rao, B. P., & Kim, C. (2014). Magnetic nanoparticles: Preparation,
physical properties, and applications in biomedicine. Journal of Industrial and
Engineering Chemistry, 20(4), 1325–1335.
Islam, M. S., et al. (2021). Conventional to green synthesis of magnetic iron oxide
nanoparticles; its application as catalyst, photocatalyst and toxicity: A short review.
Inorganic
Chemistry
Communications,
